Abstract
Marked changes in the incidence of anencephalus have repeatedly been observed in both Birmingham and Scotland (e.g. MacMahon, Record, and McKeown, 1951; Leek, 1966). These seem, however, to be the only parts of the British Isles where inci dence over long periods has been studied; and even here it is not clear how much of the variation observed was due to environmental influences, and how much to alteration of the genetic constitution of the population by immigration. In this note we compare the figures previously recorded with data for Dublin, where immigration has not occurred on the same scale.
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