Abstract
Changes in the ratio of two molecular species of ethanolamine plasmalogen, Pl-LE-1 and Pl-PE-2, of human central nervous system myelin during development were measured by a TLC procedure. The ratio was found to decrease sharply with age up to 6 months as a result of an increase in the amount of Pl-PE-2, believed to be a unique myelin lipid with 18:1 chains in both positions of the glycerol. The ratio continued to decrease gradually with age and did not reach the adult level until an age of 17 years.
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More From: Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
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