Changes in the central nervous system in children with rheumatism

Abstract

The question of the state of the central nervous system in children with rheumatism has long attracted the attention of numerous researchers (V. V. Mikheev, E. A. Bley, R. M. Pen, Z. M. Zemlyakova, M. A. Izrailskaya, etc.). Forms of rheumatism with distinct neurological disorders were usually studied. The state of the nervous system in cardiac and articular forms of rheumatism, proceeding without sharp neurological symptoms, has not yet been fully studied clinically, and almost not studied pathomorphologically. Until now, there is no consensus about the nature of changes in the autonomic division of the central nervous system in this disease. The aim of this work is to conduct a clinical study of the state of the central nervous system in children with cardiac and articular forms of rheumatism in the active phase of the disease, as well as to study pathomorphological changes in the brain and spinal cord in patients who died from these forms of rheumatism.