Abstract
BackgroundThe relationship between diabetes and academic performance have been of great interest to researchers during the year to date. Many studies have been conducted to discover this relationship during three recent decades. But, evaluation of the structural changes of brain in the context of diabetes is of paramount importance especially in children and adolescents.MethodsThis study is a systematic review conducted to investigate the structural changes in the central nervous system in children and adolescents living with diabetes. Among about 500 papers published in this area in Pubmed and SCOPUS, 13 articles in the field of assessing structural changes in the central nervous system in children and adolescents with diabetes mellitus were entered into the evaluation process.ResultsAs can be seen in these studies, a huge proportion of structures of the central nervous system have been affected by diabetes that include different areas of gray and white matters. In the majority of these studies, it has become clear that high glycemic changes, especially recurrent hyperglycemic attacks are very seriously associated with structural changes in the brain.ConclusionIt seems the findings of this review can positively aid other researchers to develop medical guidelines to prevent or resolve the brain changes in central nervous structure and consequently cognitive impairments in children and adolescents.
Highlights
The relationship between diabetes and academic performance have been of great interest to researchers during the year to date
It should be noted that a large number of published articles on the subject of diabetes insipitus were excluded at this stage
A considerable number of articles were excluded at this stage. Those articles examining the structural changes in the brain due to diabetic ketoacidosis, as one of the most important neurological complications in pediatric diabetes, were excluded
Summary
The relationship between diabetes and academic performance have been of great interest to researchers during the year to date. Evaluation of the structural changes of brain in the context of diabetes is of paramount importance especially in children and adolescents. Very few studies have addresses the relationship between diabetes and cognitive impairment, academic performance, and its compliance with the structure of the nervous. With the development of functional imaging techniques in recent years, the changes in the performance of different areas of the central nervous system in children and adolescents with diabetes are evaluated with a greater precision [4]. Evaluation of the structural changes of brain in the context of diabetes is of paramount importance. The detection of such relationship may offer an open window to identify the mechanism of cognitive changes in children and adolescents with diabetes and to design effective interventions to prevent these changes. The authors of the present paper are trying to prevent structural changes in children and adolescents living with diabetes using this pathway
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