Changes in monochromatic higher-order aberration in different pupil sizes with accommodation in Tetraflx accommodative intraocular lens

Abstract

Objective To study the effect of accommodation on monochromatic higher-order aberration in different pupil sizes in Tetraflx accommodative intraocular lens (AIOL). Methods Using a Ray-tracing method, the root mean square (RMS) values of higher order aberrations for each subject with pupil diameters of 4.0, 3.0, 2.0mm were calculated. Results RMS values of total high-order aberrations, total coma, total spherical, and total trefoil aberrations significantly decreased as pupil size decreased in the relax state. In 4.0, 3.0, 2.0mm pupil sizes, the RMS values of total trefoil aberrations was the highest item of HOA in the relaxed state, which would take the optimization aberrations probably; and total coma and total spherical was higher in this state. The 4th spherical aberration decreased and changed from positive to negative with increasing accommodation over 4.0mm size, whereas it changed inversely under all accommodative levels over the 2.0mm pupil sizes. Conclusions In 4.0, 3.0, 2.0mm pupil sizes, dramatical trends amongst the HOA under all accommodative levels are demonstrated to understand the regulatory mechanism of Tetraflex AIOL. Most of intraocular HOA induced by accommodation decreased the compensating action might to be present among them under accommogative stimuli. Key words: iTrace system; Wavefront; Intraocular lens; Accommodation