Abstract
The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea hypopnea syndrome (OSAS) is called overlap syndrome (OS). Compared to single COPD or OSAS patients, OS patients have more severe hypoxemia associated with nocturnal sleep, showing more severe impairment of lung function and pulmonary hypertension, and the prognosis is worse. It is of great clinical significance to improve the understanding of OS and to make the diagnosis and treatment timely of OS patients. Microalbuminuria (MA) is an important indicator of vascular endothelial dysfunction and an independent risk factor for cardiovascular disease. It has important reference value for judging the occurrence, development and prognosis of the disease. Therefore, to study the change of microalbuminuria and its correlation with clinical parameters in patients with OS may have important clinical significance on the prognosis of overlap syndrome patients. The changes and clinical significance of microalbuminuria in patients with overlap syndrome are summarized as follows. Key words: Pulmonary disease, chronic obstructive/CO; Sleep apnea, obstructive/CO; Albuminuria; Review
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