Change in brain electrical activity connectivity in migraine patients without aura

Abstract

Objective: In this study, we consider how the structure of the brain EEG activity changes in patients with migraine, compared with virtually healthy volunteers without complaints of acute or chronic headache. Materials and Methods. The study of the connectivity of EEG activity was carried out on the basis of an objective assessment of pairwise synchronization between different recording channels, for which we used a method based on wavelet bicoherence. Results. Within the framework of the performed experimental study, we demonstrated an increased reactivity in the structure of connections in brain electrical activity of the patients experiencing a weak visual impact. Conclusion. A prospective study could determine the value of the described diagnostic procedure in support of the clinical decision on appropriate pharmacological and non-pharmacological prophylactic measures.