Challenging Expectations: A case of highh-grade serous oavarian carcinomai in a young with unespected mutations

Abstract

Despite the low prevalence, ovarian cancer has high mortality. More common in elderly patients, is mostly diagnosed late, which leads to high recurrence and a low five-years-disease-free-survival Carcinoma is the most common type, and the high grade serous carcinoma (HGSC) subtype stands out in terms of aggressiveness. Whereas genetic mutations would be responsible for this difference, it was proposed a tumor classification model, which considers the main genetic changes found. Here we describe the genetic associations observed in young patient with HGSC and her clinical outcome.