Abstract

The ideal ophthalmic drug delivery system must be able to deliver the effective therapeutic concentrations in the target tissues for the intended duration with minimal adverse effects. Successful tissue-targeted delivery of ocular drugs is a challenging task for pharmaceutical scientists. The principal reasons are inherent and unique anatomical and physiological differences among ocular tissues. Ocular drug delivery is restricted by the barriers protecting the eye. The chief ocular membrane barriers are located in the cornea and conjunctiva of the eye which can significantly affect drug entry into the eye.

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