Abstract
Chaetone G (1), a new dibenzo[b,e]oxepinone, along with the known derivative 2, 5α,8α-epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol, and zeorin were isolated from the insect pathogenic fungus, Aschersonia luteola BCC 31749. The structure of 1 was elucidated based on the analysis of NMR spectroscopy and mass spectrometry. 5α,8α-Epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol exhibited antibacterial activity against Bacillus cereus with IC50 3.3μg/mL and also showed cytotoxicity toward NCI-H187 and Vero cells.
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