CFTR channels and wound healing. Focus on “Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair”

Abstract

cystic fibrosis (CF) is caused by severe loss-of-function mutations in the CFTR chloride channel ([9][1]). The predominant life-limiting pathology in CF patients is recurrent bacterial infections in the airways, which is attributable at least in part to reduced mucociliary clearance by the