Cerebrovascular manifestations of familial Mediterranean fever

Abstract

This article provides an overview of modern concepts of cerebrovascular manifestations of familial Mediterranean fever (FMV), also known as periodic disease, and describes own clinical observation. Despite the relative infrequency of cerebrovascular accidents in the structure of the clinical phenomenology of FMV, common pathogenetic aspects of these diseases indicate the need for a detailed examination of patients with suspected FMV. In addition, insufficient awareness of physicians about autoinflammatory diseases (of which FMV is a prominent member) underlines the need to include FMV in the spectrum of differential diagnosis of ischemic stroke, including taking into account national characteristics.