Abstract
Data are reported regarding electrolyte levels in plasma and cerebrospinal fluid (CSF) of 62 mentally defective children. The mean levels of the entire group and of various subgroups are not significantly different from normal population means. One case of chronic hypernatremia was detected with persistent elevation of plasma and CSF sodium and chloride. Correlational studies revealed CSF sodium and magnesium to be significantly related to plasma levels of these cations, while CSF potassium, calcium, and chloride were independent of plasma levels. The lack of an expected correlation between plasma and CSF chloride may indicate abnormal blood-brain barrier transport of chloride in some of these patients.
Published Version
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