Abstract
Measurements of cerebral hemodynamics and metabolism were made by the nitrous oxide method in 36 diabetic patients, Considering the factors of blood pressure, the author cmpared the cerebral hemodynamics in diabetics with those in non-diabetics. In the normotensive group, the mean value of cerebral vascular resistance in diabetics was significantly higher than that in non-diabetics. In the hypertenvive group, the mean value of cerebral blood flow in diabetics was significantly lower than that in non-diabetics.These significnt difference of cerebral hemodynamic changes was observed remarkably in younger group (under 29 years old in normotensive group ; under 39 years old in hypertensive group), and not observed in elderly group.These facts revealed that cerebral hemodynamic damages in diabetics were observed from younger generation than in non-diabetics.It is suggested that these cerebral hemodynamic damage is due to the arteriosclerotic change of cerebral blood vessels.In non-treated group of diabetics, cerebral hemodynamic damage was observed with lapse of duration of diabetes, but not observed in treated group.The clinical importance of these studies were discussed.Cerebral glucose metabolism of diabetic patients maintained normal value.
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