Cerebral blood flow and cerebral saturation in head injury. Comparison of CT perfusion and cerebral near-infrared oxymetry

Abstract

Background. The purpose of this study was to determine the relationship between cerebral tissue oxygen saturation and cerebral blood volume in patients with traumatic brain injury.Materials and methods. Perfusion computed tomography of the brain was performed in 27 patients with traumatic brain injury associated with simultaneous SctO2 level measurement using cerebral near-infrared oxymetry. The mean age of the injured persons was (34,5±15,5) years, 14 men, 13 women. The Injury Severity Score (ISS) values were 44,7±8,3 (25–81). The Glasgow Coma Score (GCS) mean value before the study was 10,3±1,9(5-13).Results. SctO2 varied between 51 and 89%, mean (62,1±8,3)% (left frontal lobe) and (61,3±5,1)% (right frontal lobe). Cerebral blood volume (CBV) values were (2,3±0,63) ml/100 g, cerebral blood flow (CBF) was (31,7±13,4) ml/100 gЧmin, mean transit time (MTT) values were (5,3±3,4) s, the time to peak (TTP) was (21,2 ± 2,1) s.Conclusions. Statistically significant correlation of SctO2 levels and cerebral blood volume (CBV) levels (P<0,000001) was found. There was no statistically significant correlation between brain tissue oxygenation and other parameters of the brain perfusion.