Abstract

The cephalostatin field started off with the seminal publication of Pettitet al.in 1988 describing structure and biological activity of cephalostatin 1 (1) (84).Since then several reviews have covered the activities regarding isolation, structure elucidation, biological activities, and synthetic efforts up to 1995 (1,2,34–36,54,111). This account will focus on the synthesis and biological activity of cephalostatin analogues as published until early 2002. The authors understand the purpose of this review to provide a complete overview of the cephalostatin/ritterazine analogue field. However, this article will in parts be biased to describe some work of the Winterfeldt group in more detail, based on the personal experience of the authors.

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