Abstract

Central giant cell lesions (CGCL) are proliferative nonneoplastic lesions more frequently presented in young female patients. Treatment often requires aggressive resection, which leads to major defects of the jaws. The authors present a CGCL case report treated with intralesional corticosteroid injection. A 24-year-old woman presenting no important medical condition had a chief complaint of a painless expansion swelling in the teeth 34 to 36 region, without alteration on oral mucosa color. Radiographically, a multilocular, radiolucent, well-defined margin measuring about 5 × 6 cm was identified. The incisional biopsy was performed to establish CGCL histologic diagnosis. The patient was successfully treated with 10 sessions of intralesional administration of corticosteroid (triamcinolone acetonide + articaine), distributed in all lesion extensions with a 15-day interval between them. Subsequently, a peripheral ostectomy was done. Follow-up with no signs of recurrence was performed, presenting a good prognosis.

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