CENTRAL AORTIC PRESSURE ESTIMATED BY RADIAL APPLANATION TONOMETRY IN HYPERTENSIVE PULMONARY OEDEMA: PP.8.331

Abstract

Background: Radial applanation tonometry can do an accurate, noninvasive estimation of central aortic pressure profile and variables like central pulse pressure, aortic augmentation index are closely related to the presence of left ventricular hypertrophy, diastolic dysfunction, heart failure and mortality in hypertensive patients. The aim of the study was to determine central aortic pressure profile and its prognostic value in hypertensive pulmonary oedema. Methods: 30 patients in group A, aged 40–80 years, diagnosed with hypertensive pulmonary oedema were included in our study. A standard transthoracic echocardiogram was performed for left ventricular EF, myocardial mass, diastolic function and radial applanation tonometry, everything comparing with in 30 normal (group B) subjects in the same age group. Results: In group A, the average Ejection duration was 34+/-3% (p = 0,05) lower than group B and correlated with the diastolic dysfunction of the left ventricle (p = 0,01). The aortic augmentation pressure, augmentation index were higher in group A (p = 0,01). Central aortic pressure showed a slight increase in augmentation index- average 47+/-2% (p = 0,04) with a normal ejection duration (35,7%). The augmentation index correlated significantly with myocardial mass. Conclusion: Central aortic pressure profile is higher in hypertensive pulmonary oedema. A higher aortic augmentation index and a normal ejection duration are closely related diastolic dysfunction and myocardial mass of the left ventricle and therefore may become markers of prognosis for hypertensive pulmonary oedema. Normal values: Aortic pulse pressure - 37–57 mmHg Augmentation index -22–45% Aortic augmentation pressure = 12–25 mmHg Ejection duration- 31–37%