Abstract
Cellular Responses to Chondroitin-6-Sulphate Releasing Brushite Bone Cements
Highlights
There is a wide range of bone grafting techniques used in the practice of implant dentistry
Brushite bone cement is a more recent calcium phosphate material that appears to be superior for the purpose of bone grafting relative to hydroxyapatite because it allows new bone to be laid down more quickly
This research has conclusively shown that bone cells can grow on brushite cement alone and on brushite cements containing varying concentrations of chondroitin-6sulphate
Summary
There is a wide range of bone grafting techniques used in the practice of implant dentistry. Those with particular ethnic and religious beliefs are unsuitable for bone grafting with these materials (Wenz 2001, Hämmerle et al 2012). On-going research in the field of bone grafting strives for a safe, predictable, efficient material and technique that minimises morbidity for the patient while optimising the potential benefits (Buser et al 2013). While traditional autogenous bone grafting techniques do offer considerable biological advantages for patients, they are associated with increased morbidity and likelihood of complications (Misch and Misch-Dietsh 2008). Alloplastic bone grafting materials do address many problems associated with the other non-autogenous materials and have a distinct advantage (von Arx and Buser 2006, Miron et al 2013). Like other autogenous alternatives concerns have been raised about the amount and the rate at which they are replaced by the recipient’s natural bone (Donos et al 2008, Jensen et al 2013)
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