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Abstract
The cellular slime mold Dityostelium discoideum offers a convanient system in which to investigate the biochemical events that underlie the formation of two different cell types during development. Both morphological and biochemical evidence suggest that cyclic AMP plays a key role in the patterning of prestalk and prespore cells in this organism. The antagonistic distribution of adenylate cyclase and phosphodiesterase offers the potential for establishing a gradient of cyclic AMP across the two cell types.
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