Abstract
Background Plasmodium vivax Merozoite Surface Protein-1 (MSP-1) is an antigen considered to be one of the leading malaria vaccine candidates. PvMSP-1 is immunogenic and evidences suggest that it is a target for protective immunity against asexual blood stages of malaria parasites. This study aims to evaluate the acquired cellular and antibody immune responses against PvMSP-1 in individuals exposed to malaria infections in a Brazilian malaria endemic area.
Highlights
Plasmodium vivax Merozoite Surface Protein-1 (MSP-1) is an antigen considered to be one of the leading malaria vaccine candidates
Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in a Brazilian endemic area in northeastern Amazon
This study aims to evaluate the acquired cellular and antibody immune responses against PvMSP-1 in individuals exposed to malaria infections in a Brazilian malaria endemic area
Summary
Evelyn Kety Pratt Riccio, Paulo Renato Rivas Totino, Irene Silva Soares, Maurício Martins Rodrigues, Cláudio Tadeu Daniel Ribeiro, Maria de Fátima Ferreira da Cruz1*. From Challanges in malaria research: Core science and innovation Oxford, UK. From Challanges in malaria research: Core science and innovation Oxford, UK. 22-24 September 2014
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