Abstract

ABSTRACT Virginie Hamel is a co-Group Leader and Senior Lecturer in the Department of Molecular and Cellular Biology at the University of Geneva (UNIGE) in Switzerland. She completed her PhD with Iain Mattaj at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, studying nuclear envelope re-assembly. To gain experience with bioimaging, she joined Pierre Gönczy's laboratory at the Swiss Institute for Experimental Cancer Research (ISREC) in Lausanne as a postdoc and later became a Staff Scientist. There, she began researching centriole assembly, combining biochemical approaches and super-resolution microscopy with expertise in structural biology from her partner in the lab and in life, Paul Guichard. In 2015, Virginie and Paul started their joint Centriolar Architecture lab at UNIGE, focusing on the structural cell biology of centrioles. Their development of advanced expansion microscopy (ExM) methods has helped unravel the roles of centriolar proteins in human disease and visualise cytoskeletal organisation in diverse eukaryotic cells. For our Special Issue on Imaging Cell Architecture and Dynamics, we spoke with Virginie over Zoom about her career, the benefits of running a joint lab with her partner, and the exciting advances being made with techniques like ExM.

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