Cell ‘mechanomics’ A novel approach for precision nanomedicine in cancer

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Cell ‘mechanomics’ A novel approach for precision nanomedicine in cancer The project goal is to provide an integrative approach for the rational and personalised design of drug carriers in cancer, using the mechanical properties of cells and particles as the main principle for drug targeting— based on cell uptake. Our unique approach uses physical differences between normal and cancer cells that can define the capacity of a given particle to be engulfed by a deformable cell in order to promote specificity of therapy. In the project, we aim to establish a correlation between cancer cell deformability, malignancy and ‘phagocytosis’. The project includes advanced technologies of microfluidics, nanotechnology and theoretical physical model.