Abstract
Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1) is a kind of Ig-like membrane protein, which belongs to the immunoglobulin superfamily and can be widely detected on endothelia, epithelia, granulocytes, lymphocytes and tumor cells. Over the years, with the rapid development of tumor immunology, it is now recognized that CEACAM1 plays an important role in multiple malignant tumors, includes non-small cell lung cancer, melanoma, colorectal cancer and pancreatic cancer. This protein can mediate anti-tumor immune ability of the body and assist the immune escape of the tumors. Thus, we need to get a full understand of the functions of CEACAM1 in immunology, to reveal the mechanism of its role and to explore its possibility as a target of tumor immunotherapy. Key words: CEACAM1; Tumor immunology
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