Cavitating Mesenteric Lymph Node Syndrome and Enteropathy-Associated T Cell Lymphoma as First Manifestation of Celiac Disease

Abstract

Celiac disease (CD) is a common systemic disease, affecting about 1.0% of the population. Classical presentation includes malabsorption syndrome and deficiencies of macro-/micronutrients. Patients with undiagnosed CD may be referred to hematologists with different hematologic issues, including anemia, thrombocytosis, thrombocytopenia, leukopenia, venous thromboembolism, hyposplenism, and IgA deficiency. CD imposes an increased risk of various lymphomas, especially intestinal T- and B-cell lymphomas. Enteropathy-associated T-cell lymphoma (EATL) is a rare and aggressive disease with poor prognosis and often fatal complications. Here we present a case of EATL associated with cavitating mesenteric lymph node syndrome as a first manifestation of undiagnosed CD.