Abstract
Coronavirus disease 2019 (COVID-19) could be complicated by venous or arterial stroke. However, to the best of our knowledge, there is a limited number of cases reported to develop cavernous sinus thrombosis (CST) after COVID-19. Herein, we present a 61-year-old diabetic male with persistent pain in his right forehead and periorbital region after COVID-19 pneumonia and diagnosed with CST after developing diplopia and periorbital ecchymosis. Magnetic resonance imaging revealed right maxillary sinusitis, inflammatory changes extending through the medial wall of the orbit and medial rectus muscle. CST was diagnosed. The mucormycosis was diagnosed by examining the extracted material with surgical thrombectomy. Appropriate surgical intervention, anticoagulant, and antifungal treatment yielded in a significant improvement in pain and orbital movements. In conclusion, in the presence of prothrombotic risk factors, like uncontrolled diabetes or recent COVID-19 infection, the physicians should consider the probability of CST in the differential diagnosis of persistent periorbital headache.
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