Abstract
Summary. Introduction. Acute thrombosis of deep veins (DVT) of the lower extremities is a pathology that requires immediate treatment, but most thrombolytics do not work effectively, except for catheter-directed thrombolysis.
 Research aim. Rationalization of DVT treatment, determination of the catheter thrombolysis method as the most effective way to eliminate proximal thrombosis of deep veins.
 The analysis was based on the results of the treatment by different thrombolytic drugs the patients with the given pathology.
 Results and discussion. According to the analysis the most effective method of DVT treatment is catheter-guided administration of streptokinase, because streptokinase is the most effective anticoagulant, and its local action on the mass of the thrombus allows for complete elimination of the thrombus in a relatively short time without the counter allergic reaction to the infusion of streptokinase.
 Conclusions. Catheter-directed infusion of streptokinase as a method of treatment of acute thrombosis of the lower extremities has significantly better treatment results compared to other methods of treatment of this pathology.
Highlights
Venous thromboembolic complications (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a hot problem in modern medicine due to one of the frequent causes of mortality and invalidation [1]
Catheter-directed infusion of streptokinase as a method of treatment of acute thrombosis of the lower extremities has significantly better treatment results compared to other methods of treatment of this pathology
Lower extremity DVT and PE are considered as two aspects of the same pathological process — venous thromboembolism (VTE), which causes high morbidity and mortality [1, 2, 4]
Summary
According to the analysis the most effective method of DVT treatment is catheter-guided administration of streptokinase, because streptokinase is the most effective anticoagulant, and its local action on the mass of the thrombus allows for complete elimination of the thrombus in a relatively short time without the counter allergic reaction to the infusion of streptokinase
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