Abstract
Organophosphate compounds are used as commercial insecticides and applied as aerosols or dust. Consuming these compounds intentionally or unintentionally lead to dangerous conditions even to fatality. The most common obstacle in treating organophosphorus poisoning is the availability of sufficient medical care, equipment to provide proper emergency care observed in rural areas where there is a lot of gap between intensive care and acute care. Atropine use is as an antidote in organophosphorus poisoning. The dose of atropine mainly depends on the organophosphorus toxic doses. Atropine is a competitive antagonist of acetylcholine at the muscarinic postsynaptic membrane. Atropine blocks all the muscarinic effects in the body. This study presents a case of organophosphorus poisoning treated with atropine leading to atropine psychosis. Patient’s conditions, outcomes, and improvements are studied.
Highlights
Organophosphorus compounds are available as dust, granules, or liquids, and some products are required to diluted with water before use [1]
Physostigmine can be given as an antidote by slow intravenous infusion rapidly reduces the delirium, coma caused by large doses of atropine
After patient was responding to the surroundings yet agitated suggested for Neurophysician consultation when patient was in intensive care unit (ICU) while patient was showing signs of atropine inducing psychosis like non-responsive dilated pupils, delirium, neck muscle, proximal weakness, patient has a within the range of blood pressure, but shown slight tachycardia, blurred vision, chest B/L mild crept
Summary
Organophosphorus compounds are available as dust, granules, or liquids, and some products are required to diluted with water before use [1]. CASE REPORT A female patient of age 25 years old weighing 55 kg admitted to the emergency department on alleged consumption of organophosphorus compound. She has got a pesticide containing organophosphorus from nearby field workers who were using it as a spray on the crop. After patient was responding to the surroundings yet agitated suggested for Neurophysician consultation when patient was in intensive care unit (ICU) while patient was showing signs of atropine inducing psychosis like non-responsive dilated pupils, delirium, neck muscle, proximal weakness, patient has a within the range of blood pressure, but shown slight tachycardia, blurred vision, chest B/L mild crept. Blurred vision, altered sensorium, pinpoint pupils, and mental changes continued until the 10th day of hospitalization
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