Abstract
Juvenile xanthogranuloma is an unusual, self-limiting dermatological disorder occurring especially in infants, late childhood and rarely in adults. It belongs to the broad group of non-Langerhans cell histiocytosis. It usually appears as solitary or multiple papules, macules or nodules several millimeters in diameter with the head and neck being the most common site of involvement and vulva being the rare site. We report two cases of juvenile xanthogranuloma in an 18 months old female and 18 months old male. The female presented with three yellow papules measuring 2-3 mm in diameter around vulva region since 4 months. Similarly, the male presented with multiple tan-orange color macules on head and forehead measuring 3-4mm in diameter since 6 months. In both the cases, a biopsy without total excision was performed. The clinical and histopathological evaluation confirmed the diagnosis of juvenile xanthogranuloma. In childhood, juvenile xanthogranuloma is necessary to differentiate from another probable differential diagnosis by biopsy.
Highlights
Juvenile xanthogranuloma (JXG) is an unusual disorder belonging to the group of non-Langerhans cell histiocytosis [1]
This article presented a female and a male diagnosed as juvenile xanthogranuloma confirmed by biopsy
The location of cutaneous lesions in case A in vulva is rarely reported in the literature in children the location of case B on the head and forehead, is the commonest location of JXG
Summary
Juvenile xanthogranuloma (JXG) is an unusual disorder belonging to the group of non-Langerhans cell histiocytosis [1]. In the first two decades of life, most cases of xanthogranulomas present as multiple, self-limited, cutaneous lesions in children, and has been defined as juvenile xanthogranuloma [2, 3]. It is clinically characterized by asymptomatic single or multiple papules, macules or nodules usually tan-orange color ranging from several millimeters in diameter which does not require treatment [4]. The presence of lesions on the trunk, extremities, and extracutaneous locations has been reported, the common sites include the head and neck [4, 5]. This article presented a female and a male diagnosed as juvenile xanthogranuloma confirmed by biopsy
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