Abstract
Extralabel treatment of mastitis in dairy cows may be of questionable efficacy and legality. This study examines the extralabel use of an antibiotic mixture compounded by a veterinary clinic to treat cows for mastitis on 3 farms. The mixture contained penicillin, spectinomycin and dexamethasone. The literature and regulations regarding use of each of these drugs for treatment of mastitis are discussed. The requirements established by the Animal Medicinal Drug Use Clarification Act (AMDUCA) were not met. The objective of this report is to increase awareness of risks involved in extralabel use of antibiotics. Adulteration of the compounded product, and potential for drug residues in foods from animal origin, are of particular concern.
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