Abstract
Orofacial granulomatosis (OFG) is an uncommon condition that presents as non-tender, non-pruritic, chronic oral labial swelling. It is a diagnosis of exclusion, and requires a full systemic workup to exclude other causes of granulomatous inflammation, such as Crohn’s disease, sarcoidosis, and tuberculosis. The cause of OFG is unknown, and there is significant debate as to whether it is in fact a separate entity, or merely an initial and/or localized form of Crohn’s disease (CD). We describe a case of OFG in a 37 year-old male from Newfoundland, Canada, and discuss in detail the systemic workup, and the reasoning behind the diagnosis. A photo of the lesion is included, as well as histopathology showing non-caseating granulomatous inflammation. Short discussions of etiology and treatment options are also included.
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