Case Report: Fibrosarcoma in Maxilla in Youngest

Abstract

Abstract- Fibrosarcomas are rare but highly fulminant and aggressively malignant neoplasm whichoccurs as a result of mutated spindle-shaped fibroblasts. According to WHO, they are soft tissuesarcoma commonly present seldom at cutis. The etiology of such a malignancy is obscurednevertheless it has several predisposing factors like pre-existing pathology but the commonest ofthem is radiation. Mesenchymal malignancies were initially over-diagnosed and were the epicenter ofdiagnostic dilemma to the pathologist, but with the advent of Vimentin staining andimmunohistochemistry, the diagnostic front has fairly advanced for fibrosarcomas. Incidence ofFibrosarcoma in Maxilla accounts for less than 0.1%, when compared to other head and neckmalignancies, and is predominantly found between 2nd to 6th decades of life. Various approacheshave been documented in the literature regarding its treatment, but aggressive surgical excisionremains the mainstay of treating Fibrosarcomas. The role of adjuvant medicinal therapies have beenwell debated but do have a conclusive outcome. Through this article, we want to highlight anddocument a case, which occurred at an exceptionally young age, at a site that had no predisposingfactors but has proven immunohistochemical diagnosis and was rapidly fulminating and aggressivelymalignant. The preoperative diagnosis of the patient was inconclusive reporting it to be amesenchymal tumor, therefore, the patient was treated with the intraoral approach for wide surgicalresection. The surgical specimen was subjected to immunohistochemistry with Vimentin stainingwhich reported it to be a Fibrosarcomas, therefore the patient was advised chemotherapy, yet theprognosis is guarded.