Abstract

BackgroundVaricella-zoster virus (VZV) is a known cause of aseptic meningitis, with a predisposition for an immunocompromised population. A dermatomal rash usually accompanies aseptic meningitis secondary to VZV.Case presentationWe report the case of a 31-year-old male with a history of chickenpox in childhood and recent shingles who presented with severe frontal headaches secondary to VZV meningitis. The patient had also recently received the measles-mumps-rubella (MMR) vaccine. He recovered without any neurological sequala.ConclusionThis case report describes an immunocompetent patient with recent MMR vaccination who developed aseptic meningitis secondary to VZV without any dermatomal involvement (Zoster Sine Herpete).

Highlights

  • Varicella-zoster virus (VZV) is a known cause of aseptic meningitis, with a predisposition for an immunocompromised population

  • We present the case of a young male who presented with headaches and was diagnosed with aseptic meningitis secondary to VZV reactivation without any dermatomal involvement

  • The reactivation of dormant VZV from spinal ganglia from a prior infection is attributed to zoster [10]

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Summary

Introduction

Varicella-zoster virus (VZV) is a known cause of aseptic meningitis, with a predisposition for an immunocompromised population. VZV infection can lead to aseptic meningitis in both immunocompetent and immunocompromised patients. VZV can present without a dermatomal rash (Zoster Sine Herpete). We present the case of a young male who presented with headaches and was diagnosed with aseptic meningitis secondary to VZV reactivation without any dermatomal involvement.

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