Carnosine and anserine contents of different parts of normal and denervated plantaris muscle of rabbits

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The carnosine content of normal rabbit plantar muscle rises from 76–107 mg% in its proximal one-fifth to 114–159 mg% in the distal one-fifth of its length. There was a similar, although less well marked gradient in anserine content, which was higher at the distal than the proximal end of the muscle, but which varied irregularly in the middle sections. The carnosine content of the muscle fell to from a third to a quarter of the normal value 12–14 days after denervation, and it was then distributed uniformly along the muscle. Denervation had very little effect on the distribution of anserine in the muscle.