Abstract
Background and Aims : The 2019 ESC/EAS Guidelines acknowledge the substantial lifetime atherosclerotic cardiovascular disease (ASCVD) risk conferred by very high inherited Lp(a) levels. The UK Biobank data demonstrated a linear gradient in risk across the Lp(a) distribution, without a threshold effect. As this risk is lifelong, early diagnosis and intervention may yield significant benefits for CVD prevention. We studied the characteristics of patients with hyperlipoproteinaemia(a) and ASCVD.
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