Abstract
Congenital heart disease is recognized to occur in families, i.e., in a parent or grandparent and in 1 or more siblings. The occurrence of congenital heart disease in both husband and wife must indeed be rare, and even more so is the occurrence of cardiac valve replacement in both husband and wife. Such was the case, however, in 2 recently studied patients. Each had the most common congenital heart disease that occurs in their sex, namely, mitral valve prolapse in women and bicuspid aortic valve in men. 1
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