Abstract

Accurate segmentation of myocardial in cardiac MRI (magnetic resonance image) is key to effective rapid diagnosis and quantitative pathology analysis. However, a low-quality CMR (cardiac magnetic resonance) image with a large amount of noise makes it extremely difficult to accurately and quickly manually segment the myocardial. In this paper, we propose a method for CMR segmentation based on U-Net and combined with image sequence information. The method can effectively segment from the top slice to the bottom slice of the CMR. During training, each input slice depends on the slice below it. In other words, the predicted segmentation result depends on the existing segmentation label of the previous slice. 3D sequence information is fully utilized. Our method was validated on the ACDC dataset, which included CMR images of 100 patients (1700 2D MRI). Experimental results show that our method can segment the myocardial quickly and efficiently and is better than the current state-of-the-art methods. When evaluating 340 CMR image, our model yielded an average dice score of 85.02 ± 0.15, which is much higher than the existing classical segmentation method(Unet, Dice score = 0.78 ± 0.3).

Highlights

  • Heart disease has seriously threatened human health and is one of the diseases with the highest mortality rate [1] [2]

  • We propose a method for Cardiac Magnetic Resonance (CMR) segmentation based on U-Net and combined with image sequence information

  • David et al proposed a method based on the hidden semi-Markov model (HSMM) and support vector machine (SVM), which is used to segment the main heart sounds in the electrocardiogram (PCG) [14]

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Summary

Introduction

Heart disease has seriously threatened human health and is one of the diseases with the highest mortality rate [1] [2]. Accurate and rapid diagnosis of heart disease is very important to save lives. Cardiac Magnetic Resonance (CMR) has been widely used in the diagnosis and treatment of heart disease [3] [4]. An automatic and accurate cardiac MRI segmentation method is highly desirable. A large number of methods based on deep learning have been widely used in medical image segmentation. This approach is reflected in the 2017 Automated Cardiac Diagnosis Challenge (ACDC) where the aim is to automatically perform segmentation and diagnosis on a 4D cine-CMR scan [6] [7]. Based on U-Net, FCN’s classic method of segmentation

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