Abstract
Cardiac arrhythmia There is an urgent need to better understand and localise the sources of cardiac arrhythmia in order to improve its treatment. In this project, we propose a radical new approach of applying network theory to study the mechanisms of cardiac arrhythmia. Currently, network theory has a myriad of applications throughout biology, physics and social sciences. However, it has never been applied to the heart. In this proposal, we will apply network theory to clinical data of cardiac arrhythmia, backed-up by computer simulations, to automatically detect the source of the arrhythmia for complex atrial tachycardia, atrial fibrillation and ventricular tachycardia.As we will identify possible ablation targets, the goal of this project is to improve the treatment for the patient.
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