Abstract

A specific and quantitative immunological method for determination of human erythrocyte carbonic anhydrase (H.C.A.) isoenzyme B has been used to determine the contents of enzyme in the erythrocytes from healthy persons and from subjects with thyroid disorders. The investigations have shown a statistically significant decrease of H.C.A. type B in the erythrocytes of hyperthyroid subjects and an increase of this isoenzyme in hypothyroid subjects. Correlation was found between H.C.A. type B and serum-thyroxin. The value of H.C.A. type B determination in the diagnosis of thyroid disorders is discussed.

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