Abstract
Study aimed to prepare and evaluate carbon based kajal formulation and carry out its comparative evaluation with the marketed formulations of kajal.
 Initially, carbon soot was deposited on Aloe vera mucilage spreaded on a copper plate, in specifically designed apparatus. Subsequently, sun dried plate was allowed to expose to the flame of cow ghee for 1 hr. Soot which was deposited on the copper plate was scrapped and Characterization of Soot by SEM, TEM, FTIR, XRD and EDX was carried out and kajal was prepared by adding few drops of cow ghee to it. The kajal was compared with the five marketed kajal formulations available in India, on the basis of physical characteristics their antibacterial potential was also assessed against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli.
 All the formulations exhibited almost similar physical characteristics. The prepared kajal showed pH (7.06±0.13). The antimicrobial activity of the marketed formulations was comparatively less than that of freshly prepared exhibiting zone of inhibition 13.05±0.11, 20.08± 0.13 and 22.06±0.18 mm against Pseudomonas aeruginosa, Staphylococcus aureus, and E. coli respectively. EDX spectra, revealed that the cow ghee soot have the weight percentage of carbon and copper as 79.20 and 17.10% respectively and Confirmed the absence of Lead (Pb). The eye irritation test (OECD 405) also showed no any irritation, redness, watering of the eye or swelling was not observed for prepared formulation in test animal. Prepared Kajal can be safely used for beatification and also in the treatment of eye diseases especially in pediatrics.
Highlights
Personal care products and facial cosmetics are commonly used by millions of consumers on a daily basis
The sterile agar was inoculated with the bacterial cultures separately (S. aureus, P. aeruginosa and E. coli) for 48 h, at 370C
Bores were made in the wells by using a sterile borer, and all marketed and prepared formulations (5 mg/mL solution was prepared by dissolving the test sample of Kajal in Dimethyl sulfoxides (DMSO)) and 80 μl volume
Summary
Personal care products and facial cosmetics are commonly used by millions of consumers on a daily basis. These products are directly applied to human skin and mainly produce local exposure to certain ingredients [1]. Eye cosmetics have been used since prehistoric times to emphasize and highlight the eyes to enhance perceived attractiveness and beauty [4]. Eye makeup has been used since long time to improve personal appearance, to get better selfworth or attract the interest of others. From the 1000s of years, the human being decorated their eyes by using colorful substances in order to improve their facial look. Black paints gives relief from the obtrusive sun and reflection from the sand before invention of sunglasses and Kajal was out of them!
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