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Abstract
The content of ATP, ADP, AMP and lactate in 105 bovine lenses of 1.7 to 185 months has been determined. A second preparation of 109 bovine lenses from 1.6 to 167 months was used to measure the content of inorganic phosphate. The concentration of all these substances decreases with increasing age. Extent and temporal course of the decrease vary. Results obtained are calculated by three modifications of factor analysis. It is evident that ATP stands alone in loading a factor, while all other substances and age (with opposite sign) appear as joint representatives of factors. This fact indicates that the ATP content of the lens is not a direct criterion of age but may be a consequence of age-dependent, qualitative changes in carbohydrate-breakdown. This concept is also supported by the behaviour of the ATP/ADP quotient reaching the maximum between 3 1 2 and 6 years of age.
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