Abstract
Phytochemicals from Capsicum anum L. plant extract are traditionally used to cure bronchitis. Bronchitis is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that myrcetin and quercetin can effectively deactivate the Palmitoyl-CoA hydrolase enzyme thereby interrupting the life cycle of Haemophilus influenza.
Highlights
Plants are used as medicine throughout the world and are the major resources of medicine [1]
-CDOCKER energy was calculated based on the internal ligand strain energy and receptor-ligand interaction energy. -CDOCKER interaction signifies the energy of the nonbonded interaction that exists between the protein and the ligand
The criteria for best interaction was chosen based on a) high positive value of -CDOCKER energy and b)small difference between CDOCKER energy and -CDOCKER interaction energy [7,8]
Summary
Plants are used as medicine throughout the world and are the major resources of medicine [1]. Phytochemicals present in these plants are used for treating various diseases. These plantbased chemical substances are derived from different parts of plants. The plant extracts show antimicrobial action against different microorganisms [2]. Capsicum anum L. belongs to family Solanaceae. Capsicum anum L. extract is used to cure diseases like bronchitis. The objective of the study is to identify the phytochemical responsible to cure the disease
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