Capacity of Guiding Osseous Regeneration: Periosteum Versus Mesenchymal Stem Cells

Abstract

The study was made on healthy common breed dogs on which, under general anesthesia, bone defects were made. For treatment were used scaffolds with hydroxyapatite-collagen support loaded with mesenchymal stem cells or the bone hole was covered with autologus periosteal flap. Evaluation of the healing process was made by clinical and, x-Ray exam. In guiding osseous regeneration in dog autologous periosteum has similar capacity, even better than autologous mesenchymal stem cells loaded on collagen impregnated with hydroxyapatite scaffolds.