Abstract
<p><strong>ABSTRACT. </strong><strong><em>Background</em></strong>: The success of endodontic therapy depends on an optimal biomechanical preparation, which includes removal of smear layer formed during root canal preparation. Smear layer adheres to the dentin surface and occludes the tubules, preventing the adhesion of the sealant material. It must be removed through irrigants that cause changes on the dentinal surface. Ethylenediaminetetraacetic acid (EDTA), citric acid, and tetracycline have been used as irrigants. <strong><em>Purpose</em></strong>: To identify changes in dentine after applying EDTA, citric acid, and tetracycline as irrigants, as described in available literature. <strong><em>Methods</em></strong>: In this systematic review, histomorphometric changes in dentin surface observed after using root biomodifiers, regarding application time and concentration of solution. The sample consisted of 20 articles selected from a population of 889 articles found and published between 2009 and 2016. The overall measure of results was the standard difference of dentinal demineralization depth, obtained for each solution. <strong><em>Results</em></strong>: According to the literature, the depth of demineralization is directly proportional to exposition time and concentration after application of the irrigant. Regarding other variables, such as pH, evidence was limited to draw conclusions. Thus, it is suggested there is not enough scientific evidence to support this type of study. <strong><em>Conclusions</em>:</strong> Dentinal changes that occur after using root biomodifiers depend on the length of the application time and its concentration.</p>
Highlights
Resumo: Antecedentes: O sucesso do tratamento depende de endodontia preparação biomecânica óptima, que inclui a remoção da camada de manchas formado durante conduta de instrumentação, esta camada adere à superfície da dentina e ocluir os túbulos dentinários, prevenir a aderência do material vedante e deve ser removido por soluções de irrigação, que causam mudanças na superfície da dentina
e success of endodontic therapy depends on an optimal biomechanical preparation
which includes removal of smear layer formed during root canal preparation
Summary
Se empleó una estrategia de búsqueda electrónica en la que se incluyeron estudios que evaluaran el efecto del EDTA, el ácido cítrico y la tetraciclina como agentes desmineralizantes de la dentina, así como el efecto que causan sobre esta. Los artículos incluyeron estudios experimentales y cuasiexperimentales, cuyas pruebas se realizaron in vitro, en dientes permanentes de humanos, con dentina como sustrato, y que incluyeran algunas de las siguientes variables: concentración, pH y tiempo de aplicación. Como se mencionó, artículos publicados entre los años 2009 y 2016. Los criterios de inclusión fueron: ensayos clínicos, estudios in vitro, en idiomas inglés y español, y que estuvieran disponibles. Posteriormente, se hizo el descarte de acuerdo con los criterios de inclusión y exclusión y se obtuvo un total de 20 artículos
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