Abstract
The contraction of the pharmaceutical industry has resulted in the underuse of a great deal of human capital and brainpower. This editorial appeals to pharmacologists who may be currently underemployed to volunteer their skills by contributing to the British Pharmacological Society's (BPS) Guide to Receptors and Channels (GRAC), and the NC-IUPHAR database (IUPHAR-DB). NC-IUPHAR has 60 subcommittees on specialized pharmacological areas where scientists freely give their time for articles on receptors or channels, and to populate IUPHAR-DB. These are freely available to all on the Web via a new resource: http://www.guidetopharmacology.org. The site features articles on all aspects of pharmacology, particularly new areas: microRNAs, epigenetics and transporters. One aspect that would be covered, alongside nomenclature and key pharmacology, is the drug discovery challenges in each area. Here the knowledge base from the pharmaceutical industry would be particularly valuable. In a separate editorial, Anne Hayes and Jackie Hunter discuss the scientific fallout from the recent contraction of the pharmaceutical industry, intended to stimulate further discussion concerning the best way to achieve the publication of negative data in drug discovery research: http://dx.doi.org/10.1111/j.1476-5381.2012.02215.x.
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