Abstract
The present short review covers a new class of bioactive fully functionalized calix[4]arenes representing symmetrical bolaform amphiphiles associated with two identical opposing polar regions separated by a lipophilic semi-cylindrical core. Bioactivities (anticancer, antituberculosis, anti-infective) of these cyclic tetramers are due to their special features including the multivalency, higher water-solubility, higher permeability to the cell membrane, and unique spatial pre-organization of terminal polar functional groups in the bola-topology.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
