Abstract

Evidence suggests that most myocardial infarctions result from ruptures of the atherosclerotic plaques that do not significantly compromise coronary lumen before the event. However, detection of nonsignificant coronary lesions in patients with suspected coronary artery disease without coronary angiography is challenging. We developed a calculator for nonobstructive coronary atherosclerosis based on patient gender, age, and the presence or absence of the echocardiographic signs of ascending aorta atherosclerosis and arterial hypertension. The calculator may be used for determining the probability of non-obstructive coronary atherosclerosis and for promoting compliance of patients to lipid-lowering therapy.

Highlights

  • Известно, что большинство инфарктов миокарда случаются вследствие разрыва атеросклеротических бляшек, компрометирующих просвет коронарной артерии лишь незначительно

  • Evidence suggests that most myocardial infarctions result from ruptures of the atherosclerotic plaques that do not significantly compromise coronary lumen before the event

  • We developed a calculator for nonobstructive coronary atherosclerosis based on patient gender, age, and the presence or absence of the echocardiographic signs of ascending aorta atherosclerosis and arterial hypertension

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Summary

Introduction

Что большинство инфарктов миокарда случаются вследствие разрыва атеросклеротических бляшек, компрометирующих просвет коронарной артерии лишь незначительно. Разработанный нами калькулятор с учетом наличия или отсутствия эхокардиографических признаков атеросклероза восходящего отдела аорты, артериальной гипертонии, пола и возраста пациента поможет рассчитать вероятность необструктивного коронарного атеросклероза и сформировать у пациента приверженность к липидоснижающей терапии.

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