Abstract
Calcifying odontogenic cyst (COC) is a rare, benign odontogenic lesion that sometimes may be present along with odontogenic tumors. A 22-year-old female patient was referred for evaluation of an asymptomatic swelling on the anterior maxilla with approximately 10 years of evolution. Physical examination showed firm swelling with cortical expansion within intact bluish mucosa. Computed tomography showed a unilocular hypodense image with hyperdense foci, causing loss of bone structure in the vestibular cortical and anterior wall of maxillary sinus. Diagnostic hypotheses were calcifying epithelial odontogenic tumor, ameloblastic fibro-odontoma, and complex odontoma, and incisional biopsy was performed. Microscopic analysis revealed a pathologic cavity lined by odontogenic epithelium with variable thickness, along with ghost cells, eosinophilic acellular material resembling dentinoid, and foci of dystrophic calcifications. The cyst was surrounded by a fibrous capsule. Histopathologic diagnosis was COC. The patient was referred for enucleation of the lesion for complete analysis and final diagnosis.
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