Abstract
(Abstracted from Lancet 2016;388:62–72) There is no standardized method of performing a cesarean section. The CORONIS trial randomized 5 different surgical components including blunt versus sharp entry, exterior versus intra-abdominal repair, single-layer versus double-layer closure, closure versus nonclosure of the peritoneum, and chromic catgut versus Vicryl in a 2 × 2 × 2 × 2 × 2 trial and reported short-term outcomes associated with various surgical techniques in 15,935 women in low- and middle-income settings.
Highlights
Caesarean section is one of the most commonly undertaken operations worldwide and is not done in a standardised way
In the CORONIS trial, we previously reported the short-term outcomes associated with different surgical techniques at caesarean section in 15 935 women in low-income and middle-income settings.[1]
We compared blunt versus sharp abdominal entry, exteriorisation of the uterus for repair versus intraabdominal repair, single versus double layer closure of the uterus, closure versus non-closure of the peritoneum, and chromic catgut versus polyglactin-910 for uterine repair
Summary
Caesarean section is one of the most commonly undertaken operations worldwide and is not done in a standardised way. Many of the important maternal outcomes associated with different surgical techniques will be apparent in the longer term, including the functional integrity of the uterine and abdominal scar during subsequent pregnancies and other long-term postoperative effects such as chronic pelvic pain, infertility, and symptoms related to peritoneal and bowel adhesions, including bowel obstruction. In this CORONIS follow-up study, we aimed to measure and compare the incidence of outcomes between the groups of women who took part in the CORONIS trial at least 3 years after their CORONIS caesarean section.
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