ビタミンCの安定化に關する研究

Abstract

In the synthesis of l-ascorbic acid, diacetone-2-keto-guloic acid and 2-keto-guloic acid must be prepared in the first step of its preparation. We consider that, if these compounds of the first step-are so stable and change into l-ascorbic acid in vivo, one of the authers' objects may be attained. So we prepared diacetone-2-keto-guloic acid and 2-keto-guloic acid. In this paper, the methods of prepartion of these acids, their salts, and their methyl-esters are described. The results of the feeding experiments with guinea pigs will be published in the next paper.